Lu Lu

Genetics, Genomics and Informatics
The University of Tennessee Health Science Center

Fields of interest:

Mouse genetics; quantitative trait locus, gene expression; gene network; neurodegenerative diseases, systems genetics.

Recent publications:

Junming Yue and Lu Lu editors: “Micro RNAs in neurodegenerative diseases” published by Research Signpost, 2013 ISBN: 978-81-308-0503-0

Lu L, Airey DC, Williams RW: Complex trait analysis of the hippocampus: Mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice. Journal of Neuroscience, 2001, 21:3503-3514

Lu L, Mei DF, Gustain DE, Zwas D, Homma S, Yi GH, Wang J: Exercise training normalized altered calcium handling proteins during development of heart failure. J Appl Physiology 2002, 92:1524-1530

Cook R*, Lu L*, Gu J, Williams RW, Smeyne RJ: Identification of a single QTL, Mptp1, for susceptibility to MPTP-induced substantia nigra pars compacta neuron loss in mice. Mol Brain Res. 2003, 110(2): 279-88; (co-first author)

Peirce J, Chesler EC, Williams RW, Lu L: Genetic architecture of the mouse hippocampus: Identification of gene loci with regional effects. Genes, Brain and Behavior, 2003,2:238-252

Peirce JL*, Lu L*, Gu J, Silver LM, Williams RW: A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genetics 2004, 5(1):7; (co-first author)

Chesler EL*, Lu L*, Shou S, Qu Y, Gu J, Wang J, Hsu H, Mountz JD, Baldwin N, Langston MA, Hogenesch JB, Threadgill DW, Manly KF, Williams RW: Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nature Genetics 2005, 37(3):233-42; (Co-first author)

Peirce JL, Li H, Wang J, Manly KF, Hitzemann RJ, Belknap JK, Rosen GD, Sutter TR, Williams RW, Lu L: How replicable are mRNA expression QTL? Mammalian Genome, 2006, 17(6):643-656

Mozhui K, Hamre KM, Holmes A, Lu L*, Williams RW*: Genetic and structural analysis of the basolateral amygdala complex in BXD recombinant inbred mice. Behavior Genetics, 2007, 37:223–243; (Co-corresponding author)

Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC: Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC Genomics. 2008 Sep 25;9(1):444. PMC2570693

Shen Q, Wang X, Chen Y, Xu L, Wang X, Lu L: Expression QTL and regulatory network analysis of microtubule-associated protein tau gene. Parkinsonism and Related Disorders 2009, Aug;15(7):525-31. PMID: 19233709